Samsara Vision's SING IMT: Implantable 'Miniature Telescope' Significantly Improves Distance and Near Vision in Advanced AMD Patients

Jan 14, 2025 22:15 CST Updated 22:15

Samsara Vision

Developer, Manufacturer, and Seller of Patented Implantable Ophthalmic Devices

Samsara VisionPublication in the journal 'Heliyon' on the implantable "micro telescope" ---SING IMTTreatmentClinical Research Data on Age-Related Macular Degeneration. Research and Development FindingsSING IMTThe implant improved both hyperopia and myopia with minimal impact on corneal endothelial cell density, and the safety outcomes were controllable.

Specific Research Data

At 6 months postoperatively, 97.1%, 68.6%, and 51.4% of the surgical eyesBest Corrected Distance Visual Acuity (BCDVA) ImprovementAt least 1-line, 2-line, and 3-line (n=35), the mean ± standard deviation (SD) change of BCDVA from baseline was -0.29±0.142.
The proportion of patients able to read at near distance increased from 28.6% at baseline to 97.1% at six months.
In addition to hyperopia, the study also found that corrected myopia vision significantly improved by 3 lines at 6 months post-operation.

Executive Evaluation

"Already launched in 19 countries, with over 400 patients implanted with SING IMT. More than 63% of surgeons have performed multiple surgeries, indicating increasing confidence and enthusiasm among doctors. We are pleased that this study confirms the efficacy and safety of SING IMT, and we believe our innovative device will become the standard of care for AMD patients with central vision blindness."

---Thomas Ruggia, President and CEO of Samsara Vision

Age-Related Macular Degeneration (AMD) is a chronic and irreversible eye disease. AMD is the leading cause of permanent vision loss in people aged 50 and above and the primary cause of blindness in those aged 65 and above. As many as 11 million Americans are affected by some form of macular degeneration, and this number is expected to rise to 22 million by 2050. Nearly 2 million Americans suffer from advanced AMD with associated vision loss. Although there are treatments aimed at slowing the progression of AMD and assistive devices that help individuals with decreased vision see better through magnification or increased lighting, the condition in many patients continues to deteriorate. Once it reaches the advanced stage, AMD becomes incurable.

AMD can be divided into two types: dry and wet, with the dry type accounting for about 85% of the total. Currently, there are no specific drugs available for treating dry macular degeneration; the condition can only be managed by having patients take vitamins and zinc to slow its progression. Wet macular degeneration, on the other hand, can be improved through anti-VEGF medications and surgeries that reduce blood vessel formation.

For AMD patients, the probability of the condition worsening to the advanced stage is very high, especially for those with dry AMD. Due to the lack of effective treatment technologies currently, patients with advanced AMD face the issue of complete vision loss, plunging their lives into darkness.Samsara VisionThe Second-Generation "Galileo-style"Microscope"----SING IMT, bringing hope to AMD patients, especially those with dry AMD.

SING IMT

SING IMTYesSamsara VisionThe second-generation product, which is"Galileo-style miniature telescope" implants and delivery system are designed to improve vision and quality of life for patients with advanced AMD.

SING IMTEquipped with the same ultra-precise wide-angle micro-optical components as the previous generation, and featuring an improved tactile design to create a telephoto effect. Images can be magnified 2.7 times and projected onto healthy photoreceptors surrounding the macula at the back of the eye, reducing the impact of AMD "blind spots" on central vision and enabling patients to see images they may not have been able to recognize before.

The "Galileo-type micro-telescope" implant has a maximum outer diameter of 10.8mm, is made of glass and silicone, and the silicone material can be folded and preloaded into the delivery system, so only one incision is needed during implantation.6.5mm incision (half the size of the previous generation), faster postoperative recovery. ImplantationThe surgery can be performed on an outpatient basis, with the entire procedure taking approximately 25 minutes.Including the removal of the patient's cataracts and the implantation of the "Galileo-style miniature telescope" implant in only one eye.

Nine in IrelandSING IMTDuring surgery, the endothelial cell density (ECD) loss was less than 8%, which is advantageous compared to the 23%-25% loss with WA IMT. Additionally,SING IMTPatients also reported faster recovery times.

SING IMT Demo

Samsara Vision

Samsara VisionSamsara Vision, Inc. is an innovative medical device company headquartered in the United States, engaged in the research, development, manufacturing, and marketing of proprietary implantable ophthalmic devices and technologies aimed at significantly improving vision and quality of life for patients with untreatable retinal conditions.Samsara VisionBelieve that restoring vision can rejuvenate the spirit, allowing people to reconnect with the things they love seeing and doing in life.