Home Novatim Inks $1.165B Deal for Global Licensing of First-in-Class Nanobody Bispecific ADC KY-0301

Novatim Inks $1.165B Deal for Global Licensing of First-in-Class Nanobody Bispecific ADC KY-0301

Sep 02, 2025 11:27 CST Updated 11:27
Novatim

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September 2, 2025Novatim's Official WeChat AccountNovatim"Released a press release stating that the company has reached a cooperation with Radiance Biopharma."
According to the agreement, Radiance has obtained the overseas development, registration, and commercialization rights for the nano bispecific ADC drug KY-0301.NovatimWill be eligible for$15 million upfront payment, the highest$150 millionR&D and Registration Milestone Payments and Maximum$1 billionCommercial milestone payments, and tiered sales royalties.
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According to the press release, KY-0301 is a product independently developed by Novatim.The world's first nano bispecific ADC,Obtained U.S. IND approval in 2024 and is currently conducting a Phase I dose-escalation clinical trial in China.

Compared with traditional bispecific ADCs, KY-0301 demonstrates more effective tumor tissue penetration, higher anti-tumor activity, and better safety. Based on the broad-spectrum high expression of MET and EGFR in tumors and innovative differentiated design, this drug is expected to bring new breakthroughs in the treatment of non-small cell lung cancer, colorectal cancer, and head and neck squamous cell carcinoma.

Dr. Guoxiang Wu, founder and chairman of Novatim, stated, "Through our collaboration with Radiance, we will accelerate the global clinical development and commercialization of KY-0301, providing cancer patients with innovative and highly effective treatment options more quickly."

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References:

1.Novatim Official WeChat

2.Other Public Information

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