StairPlex High-Throughput Neural Signal Acquisition System: Powering the Future of Neuroscience and Brain-Computer Interfaces

In this rapidly evolving era, the vigorous rise of neuroscience and the rapid advancement of brain-computer interface technology are expanding the boundaries of our understanding of the human brain with unprecedented power. This progress paves a broad road for innovative treatments of neurological diseases and the exploration of human cognitive potential. These cutting-edge technologies, through direct interaction with the brain, herald a fundamental revolution in the way humans interact with the world, leading us into a new epoch of technological development.

Based on this, StairMed independently developed and launchedStairPlex High-Throughput Signal Acquisition SystemAs a leader in the field of neuro-electrophysiological signal acquisition, the system has become a solid backbone for scientific research exploration. The StairPlex system, with its excellent performance, efficiently and accurately captures, analyzes, and processes various complex signals such as neuronal action potentials (Spike) and local field potential activities (LFP), providing comprehensive and in-depth solutions for neuroscience research and the practical application of brain-computer interface technology, fully meeting diversified and refined research needs.

StairPlex System Establishes a New Technological Height in Neural Signal Processing with Its Ultra-High Channel Count, Extreme Sampling Rate, and Exceptional Scalability

1. Headstage Micro Amplifier

As an important component of the Stairplex software, the Headstage micro-amplifier plays a central role in neural signal acquisition and processing. Its compact design allows research institutions to connect electrodes and acquisition devices more conveniently, enabling immediate analog-to-digital signal conversion and Type-C cable transmission, ensuring seamless data integration.

Compact and Portable:The compact size of the Headstage allows for flexible deployment in both laboratory and field research, while its discreet design minimizes experimental interference, enhancing the naturalness of experiments and the accuracy of data. The multi-channel integration feature ensures high-density, comprehensive data acquisition.

Low Noise and High Efficiency:With advanced circuit design and manufacturing工艺, the Headstage achieves ultra-low noise levels. A high signal-to-noise ratio ensures high-quality signals, while stability and high-precision amplification capabilities allow even weak neural signals to be clearly presented. Its excellent抗干扰性能 effectively resists external electromagnetic interference, ensuring signal purity.

2. StairPlex Software

Stairplex software, as a cutting-edge tool in the field of neuroscience research, provides researchers with a powerful data analysis and visualization platform through a series of innovative features. The software seamlessly integrates with high-throughput in vivo neurophysiological signal acquisition systems and is specifically designed for research institutions to optimize the acquisition, analysis, and processing of electrophysiological signals from experimental animals' brains (covering local field potentials and single-neuron action potential activities).

The dynamic visualization feature of Stairplex software is one of its highlights, revolutionizing the way data is observed and analyzed. Users can effortlessly manage the synchronized display of a large number of neural signals on a single interface, achieving unprecedented data insight capabilities.

Multi-channel Synchronous Display：The software supports real-time synchronous display of up to 128 channels, providing a comprehensive and intuitive overview of the signals, enabling users to quickly grasp the overall situation.

Extended Display Potential:To meet the demands of large-scale neural network research, Stairplex software can be expanded to support synchronous display of 1024 channels, fulfilling broader data coverage requirements.

Stairplex software is equipped with a comprehensive chain of analytical tools, covering every key step from data acquisition to advanced processing.

Stimulus-Triggered Control:Allowing users to precisely trigger external stimuli based on specific signal characteristics or preset conditions is crucial for researching neural response mechanisms and the learning process.

Electrode Impedance Test:Built-in functions instantly display impedance values of all channels, sorted by channel map, ensuring electrode stability and signal quality for accurate data acquisition.

Channel Activity Topology Map:Generate intuitive topology diagrams that display site impedance, firing rate, background noise, and positional information to help users gain a deeper understanding of the activity patterns and spatial layout of brain regions or neural networks.

Online Spike Sorting:Real-time identification and classification of neuronal firing, revealing the complex mysteries of neural coding.

The real-time analysis function of Stairplex software empowers users with the ability to process and analyze data instantly, accelerating the pace of scientific discovery.

Online Filtering:Supports multiple filtering modes such as band-pass, low-pass, and high-pass, allowing users to flexibly choose according to research needs to optimize signal quality.

Discharge Frequency Analysis:Quantify neuronal discharge activity to reveal its intensity and changing trends under different conditions.

ISI, PSTH, Spectral Analysis:Providing tools for inter-spike interval (ISI), post-stimulus time histogram (PSTH), and spectral analysis to deeply analyze the temporal and frequency characteristics of neural signals.

RMS Baseline Noise Analysis:Evaluate and monitor system noise levels through Root Mean Square (RMS) analysis to ensure data quality and the reliability of experimental results.

3. Signal Generator

As an excellent accessory of StairMed, the signal generator (NS-1.0) provides the system with a stable and reliable standard signal source (including Spike analog signals and sine waves), ensuring the smooth performance verification of the in vivo neuroelectrophysiological signal acquisition system before formal use and during periodic maintenance.

Multi-channel synchronous output:Supporting simultaneous analysis of multiple signals through different output interfaces is particularly crucial for experiments with high demands on multi-channel signal synchronization. It not only enhances the accuracy and reliability of data but also significantly improves experimental efficiency, enabling researchers to simultaneously monitor activities in multiple brain regions and gain a more comprehensive understanding of brain functions.

Accurate Signal Waveform:With the ability to generate high-precision signal waveforms, signal generators ensure measurement accuracy, reduce errors, and enhance the reliability of test results. This feature is particularly important in neuroscience research, as it can capture subtle changes in brain states, assisting researchers in decoding electrophysiological signals of the brain more accurately.

Rapid Sampling Capability:The signal generator has the significant advantage of a short sampling time, meeting the high demands for signal real-time performance and dynamic response capabilities in neuroscience research. Its high-speed sampling capability ensures the immediacy of signals, allowing researchers to capture rapidly occurring neural activities in the brain, which is of great significance for understanding the brain's immediate reactions and decision-making processes.

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