Recently, a company within the Zhongguan Village Life Science ParkBioGeometryAnd agricultural high-tech enterprisesDabeinongA Powerful Alliance to Achieve Strategic Cooperation,Jointly Build the Zhongguan Village Bio-Manufacturing Innovation Center, covering directions such as biosynthesis, proteomics, AI protein design, pharmaceutical health, artificial intelligence+, and more.
Estimated reading time: 2 minutes
BioGeometry focuses on building a generative AI protein design platform to empower the entire biomanufacturing field. Its core team is a pioneer in applying generative AI to molecular generation, having utilized diffusion models for 3D molecular structure generation as early as 2021. This team was among the first to apply diffusion generative models to 3D molecular structure generation. Their key paper, GeoDiff, was one of the top 50 most-cited papers in the AI field in 2022.In June this year,BioGeometry Releases the Latest Generative AI Protein Design Large Model GeoFlow,Can be used for two key tasks simultaneously: antigen-antibody complex structure prediction and antibody design. Unlike existing Transformer architectures, GeoFlow adopts a geometric deep learning foundational model, which can better model the relationships between atoms in three-dimensional space. In terms of generative model selection, GeoFlow utilizes the latest flow matching model. Compared to diffusion generative models, flow matching generative models are more efficient and robust in both training and inference. In the task of antigen-antibody complex structure prediction, GeoFlow's performance reaches the same level as AlphaFold3, making it the first generative AI macromolecule design model in the industry to approach the level of AlphaFold3.DBN has rich application scenarios in protein synthesis and design.BioGeometry and Dabeinong have joined forces to jointly build a synthetic biology DBTL良性循环 (Design-Build-Test-Learn cycle), and collaboratively create an integrated protein R&D solution that combines software and hardware.LargeThe organic integration of Beijing Agricultural University and BioGeometry's GeoFlow generative AI large model will produce a 1+1>2 effect., which will eventually form an innovative ecosystem for protein synthesis and design, achieving a commercial closed loop from R&D, pilot testing, scale-up, to industrialization.In the future, the platform will gather more innovative resources for protein synthesis and design, solicit and cultivate AI protein design-related innovation projects globally, form a new pattern of integrated development among large, medium, and small enterprises, and build China's agricultural Silicon Valley and a global highland for agricultural technology innovation.
