C-Wave® Coronary Intravascular Lithotripsy System Showcased at China-Brazil Cardiovascular Innovation Forum Amid IPO Filing
H&H Healthcare
R&D and Producer of Interventional Medical Devices for Heart Disease
RecentlyChina-Brazil Cardiovascular Innovation ForumSuccessfully held online. Experts from both locations jointly participated in case discussions, strategy formulation, and experience sharing through live streaming, promoting mutual exchange and cooperation in the medical field among BRICS countries.
Case Introduction
Patient, female, 70 years old.
A 10-year history of hypertension, type II diabetes, and hyperlipidemia. Admitted to the hospital for coronary heart disease due to exertional angina that has occurred in the past month.
Laboratory tests: Troponin T was mildly elevated, NT-proBNP was normal, and liver and kidney functions were normal.
ECG: Sinus rhythm, partial ST-T changes.
Echocardiogram: LA 29mm, EF 65%
Angiography shows: RCA dominance, left main bifurcation, and LAD lesion (moderate to severe stenosis).
Surgical Strategy
IVUS + IVL + Drug-Eluting Stent Implantation
Surgical Procedure
Successful puncture of the right femoral artery approach, placement of a 7 F arterial sheath, and positioning of a 7F JL3.5 guiding catheter. Planned LCA stent implantation under IVUS guidance. A Runthrough wire was passed through the proximal LAD lesion to the distal vessel, and a Sion wire was advanced into the distal LCX vessel. A 2.0*20mm pre-dilation balloon was selected for sequential dilation at the LM-LAD/LM-LCX lesion sites. IVUS examination showed localized approximately 270° calcification in the mid-LAD and distal LM.
After expert discussion, it was decided to apply the 3.0*12mm C-Wave® Coronary Shockwave Balloon to the mid-LM-LAD lesion for pre-treatment of calcified plaques. First, the balloon was delivered to the mid-LAD for four cycles of shockwave treatment, then the balloon was withdrawn to the LM bifurcation for another four cycles of shockwave treatment. During the treatment, the notch significantly disappeared and vascular compliance improved. IVUS showed multiple fractures in the calcified ring, and angiography indicated a marked improvement in left coronary blood flow. IVL achieved ideal results in the pre-treatment of calcified lesions.
C-Wave®Treated at the mid-LAD
Post-treatment IVUS Images
Angiographic Image After Treatment
Left Anterior Descending Artery (LAD): A 3.0*18mm drug-eluting stent was implanted in the middle segment of the LAD, and a 3.0*15mm high-pressure balloon was used for post-dilation within the stent in the middle segment of the LAD.
Left Circumflex Artery: A 2.5*10mm cutting balloon was used to address the proximal lesion at LM-LCX.
Left Main Bifurcation: A 3.5*30mm drug-eluting stent was implanted at the proximal segment of LM-LAD, followed by kissing balloon dilation using 2.5*15mm and 3.5*15mm high-pressure balloons.
Finally, a 4.0*8mm high-pressure balloon was used for post-dilation within the LM stent. IVUS examination showed good apposition of the LM-LAD stent, and repeat angiography revealed smooth antegrade blood flow in LM/LAD/LCX with 0% residual stenosis within the stent. The surgery was successfully completed and received unanimous praise from Brazilian experts.
Postoperative IVUS Images
Postoperative Angiography Images
Summary and Sharing
RelativelyYoung PatientsCan be selectedCoronary Artery Bypass Grafting (CABG）. Based on the patient's basic information, the choice isThrough catheterizationIt is more appropriate to proceed with the treatment. For cases with severe calcification, it is necessary to adequately assess the difficulty of the surgery. At the same time, handling such lesions requires...Good equipment to support. The application of intracavitary imaging can provide sufficient information to assess the arc and length of calcification, and coronary plaque rotational atherectomy (RA) is an effective treatment method, but it is difficult to protect the side branches during the operation, inIn cases involving bifurcations with non-extensive lesion lengthsBelow,Intravascular Shockwave Technology (IVL）It would be a better choice.
Expert Introduction
President of Xiamen University Affiliated Cardiovascular Hospital, Doctor of Medicine from the University of Hong Kong, Professor, Chief Physician, and Doctoral Supervisor.
FACC, FESC, FSCAI, National Health Commission Outstanding Middle-aged and Young Expert with Prominent Contributions, Member of the Third National Cardiovascular Disease Expert Committee, National Committee Member of the Chinese Medical Association's Cardiovascular Branch, Deputy Head of the Interventional Cardiology Group of the Chinese Medical Association's Cardiovascular Branch, Vice Chairperson of the Structural Heart Disease Professional Committee of the National Cardiovascular Disease Expert Committee, Chairperson of the Cardiovascular Professional Committee of the Association for Cross-Strait Medical Exchange, Vice Chairperson of the China Chest Pain Center Certification Committee, Vice Chairperson of the Chest Pain Professional Committee of the Chinese Medical Doctor Association, Vice Chairperson of the Hypertension Branch of the Cardiovascular Disease Management Committee of the China International Exchange Promotion Association for Medical and Healthcare, Member of the Cardiovascular Disease Expert Committee of the Geriatric Medicine Committee of the China Gerontological Society, Member of the Cardiovascular Disease Management Professional Committee of the China International Exchange Promotion Association for Medical and Healthcare, Member of the Cardiovascular Internal Medicine Physician Branch of the Chinese Medical Doctor Association, Member of the Cardiovascular Branch of the Fujian Province Chinese Medical Association.
Doctor of Medicine, Chief Physician, Associate Professor at Xiamen University, Master's Graduate Supervisor. Director of the Office of the Sub-Center of the China Chest Pain Center Regional Certification Center (Xiamen), Director of the Emergency Department and Chest Pain Center at the Cardiovascular Hospital Affiliated with Xiamen University, Member of the Structural Group of the Cardiovascular Branch of the Chinese Medical Association, Member of the Structural Group of the Cardiovascular Physicians Association of China, Member of the Structural Committee of the China Healthcare Science Association, Certification Expert of the China Chest Pain Center, Deputy Chairman of the Cardiovascular Disease Expert Committee of the Chinese Division of the International Vascular Alliance, Member of the Cardiovascular Branch of the Fujian Medical Association, Standing Committee Member of the Cardiovascular Branch of the Cross-Straits Medical and Health Exchange Association, Gold Member of the Asian Youth Structural Club. Studied at The Prince Charles Hospital (TPCH) in Australia, engaged in clinical work in cardiovascular internal medicine, coronary artery interventions, structural heart disease interventions, as well as the development, maintenance, and certification of chest pain centers.
