METiS Pharmaceuticals Named to Forbes China's 2024 Top 50 Most Innovative Companies Ahead of Hong Kong IPO Filing

Nov 13, 2024 18:31 CST Updated 18:31

METiS TechBio

AI-Driven Drug Formulation Developer

On November 13, Forbes released the "2024 Top 50 Most Innovative Companies in China" list, and METiS TechBio was honored on the list.

This year, the number of fields covered by Forbes China's Top 50 Innovative Companies has expanded from 8 last year to 12. As an increasing number of hard-tech startups secure substantial funding, China's innovation landscape is becoming more diverse.

As a representative of the leading company in the "AI + Drug Delivery" field, METiS TechBio (METiS Pharmaceuticals) has been selected for its continuous innovation technology.This year, a total of 4 pharmaceutical and health enterprises have been selected, respectively:

Baili Tianheng
Hengrui Medicine
METiS TechBio (METiS Pharmaceuticals）
Akeso Biopharma

METiS TechBio was founded and is led by Dr. Hongmin Chen, a member of the US National Academy of Engineering, along with Dr. Caida Lai and Dr. Wenshou Wang, both top scientists from MIT.AsOne of the world's leading drug delivery platformsMETiS TechBio, in the absence of open-source datasets and delivery-related algorithms, started from scratch to innovatively develop groundbreaking artificial intelligence and computational simulation algorithms for the generation and design of ionizable lipids and the design and simulation of LNP nanomaterials. By integrating world-leading high-throughput experimental techniques and animal validation platforms, METiS TechBio has established its own data and algorithmic barriers.

Currently, METiS TechBio has independently developed three major AI+ core technology platforms: AI-driven lipid nanoparticle delivery system design platform (AiLNP), AI-driven mRNA sequence design platform (AiRNA), and AI-driven small molecule formulation design platform (AiTEM). It has also established a proprietary technical route for METiS TechBio that deeply integrates dry and wet lab experiments, thereby achieving efficient drug delivery and drug discovery.

Among them, the AiLNP platform is the world's first high-throughput automated LNP design platform. By integrating rapidly advancing large models and generative AI technologies, METiS TechBio has established the world’s first METiS LipidLM lipid language model and PhatGPT lipid generation model, creating a million-level lipid library that successfully breaks through international patent barriers. Meanwhile, METiS TechBio combines innovative molecular simulation technology to simulate various microscopic processes of LNPs both in vivo and in vitro. Relying on a world-class experimental validation platform, it empowers the development of multi-organ targeted nanomaterials, achieving the successful implementation of AI + nanomaterial applications.

About "2024 Forbes China Top 50 Innovative Enterprises"

The evaluation dimensions for Forbes China's Top 50 Innovative Companies in 2024 include innovation capability (R&D investment and core independent intellectual property rights), corporate governance (the degree of digitalization and management level), corporate growth (performance of core financial indicators over the past three years), market advantages driven by innovation (market share of core products and product substitutability), and corporate social image, among others. At the same time, with a focus on innovation as the core, the development and organizational expansion of enterprises are assessed. This year, Forbes China has paid more attention to contributors who are expected to change the world and bring seemingly distant technologies into reality, evaluating them based on the progress of technology implementation and landmark events.

Attachment2024 Forbes China Top 50 Innovative Enterprises List

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