Hangzhou-based Health Ecosystem Operator 'Knowledge Matrix' Secures Tens of Millions in Series A Funding

VCBeat has learned that KNOTRIX, a health ecosystem operator, has completed its tens-of-millions-of-yuan Series A financing round. The company’s post-money valuation stands at RMB 300 million, with investors including Huayu Venture Capital, Hangzhou Liuheqiao, and Yuhang Supply and Marketing Group. Ding Zhaoliang, Founder and CEO of KNOTRIX, stated, “The funds raised in this round will be primarily used for nationwide business expansion, brand portfolio growth, and precision traffic acquisition, accelerating the enhancement of our operational capabilities in the new-media health content ecosystem.”

KNOTRIX, founded in 2020 and headquartered in Hangzhou, China, is driven by its original mission to “make health accessible.” It focuses on building a new-media health content ecosystem, leveraging high-quality content creation, precise fan engagement, rapid product iteration, and AI technology support to comprehensively provide users with authentic and effective health knowledge, products, and services.

With rising health awareness and growing health demands across society, the market size of the broader health industry is experiencing rapid growth. Meanwhile, short-video platforms have become dominant traffic hubs, reshaping public cognitive and consumption habits. Aligning with contemporary needs, KNOTRIX builds a content operation ecosystem for the broader health industry through high-quality short-video content, empowering the sector with innovative business models, cutting-edge AI technologies, and novel health products.

In the era of mobile internet, smartphones have become humanity’s “sixth organ,” with various new media platforms such as Douyin, Kuaishou, WeChat Channels, Toutiao, and Xiaohongshu vying for people’s attention.

According to data compiled by the Guanyan Data Center, in 2022, Douyin’s daily active users surpassed 700 million, with an average daily usage time per user exceeding two hours; WeChat Channels had 450 million daily active users, and Kuaishou had over 360 million daily active users, demonstrating that massive traffic is concentrated on new media platforms.

Since its inception, KNOTRIX has been dedicated to building a comprehensive IP matrix for the broader health and wellness sector. It has currently signed over 100 health science popularization IPs, covering key areas such as parenting, maternal and infant care, women’s health, and health for the middle-aged and elderly, accumulating more than 35 million followers in health-focused verticals across all major online platforms.

KNOTRIX produces over 50,000 short videos annually, accumulating more than 10 billion views across all platforms. Among these, 150 videos have surpassed 10 million views each. The platform hosts over 2,000 health-focused live streaming sessions per year, reaching a total audience of 100 million viewers across the web. The gross merchandise value (GMV) of its big health e-commerce products has exceeded RMB 800 million.

Currently, KNOTRIX is not only signing high-quality health-sector IPs, including TV hosts and infant care specialists, but has also established in-depth partnerships with over 100 major health brands and both domestic and foreign pharmaceutical companies, continuously expanding its traffic layout, enhancing the influence of health IPs, and bolstering public trust.

The development of the broader health and wellness market has been accompanied by numerous product- and operations-related issues, such as exaggerated efficacy claims, frequent negative publicity, severe product homogenization, and marketing information overload, making it difficult for consumers to select products that truly meet their needs.

To address these issues, KNOTRIX has implemented a series of measures to meet user needs—

First, KNOTRIX collaborates with leading universities and research centers, such as the College of Biotechnology and Food Engineering at Zhejiang University and the Ningbo Institute of Life and Health Industry at the University of Chinese Academy of Sciences, to develop high-quality health and nutrition solutions;

Secondly, KNOTRIX has established a rigorous traceability system for product raw materials, ensuring product quality at the source and guaranteeing the authenticity and efficacy of products to users;

Finally, leveraging its health-focused IP across the entire internet, KNOTRIX maintains continuous engagement with users, gathers authentic feedback, and fosters a healthy, trustworthy, and effective marketplace for health products.

KNOTRIX has established a comprehensive supply chain product selection system and an in-house brand incubation framework, thereby building a complete portfolio of health brands. Its brand portfolio includes co-branded and agency brands such as the “Cool Play Baby” series of diapers and the “Chun Ben Yuan” tea product line, as well as proprietary brands including “Yuan Li Ban,” “Guan Neng Li,” and “Chao Neng Yang Yu Jia.” Additionally, KNOTRIX collaborates with high-quality supply chain partners to create exclusive live-streaming studios, providing omni-channel traffic solutions for premium brands and products.

With the continuous advancement of artificial intelligence technology, an increasing number of AI tools have been developed. For instance, ChatGPT, boasting over 175 billion parameters, has provided AI-powered language support to 100 million users worldwide through advanced natural language processing algorithms. In China, models such as Baidu’s ERNIE Bot and iFlytek’s Spark Cognitive Large Model have also been launched and applied, bringing significant convenience and innovation to daily life and work.

Advancements in AI technology have provided the technical foundation for KNOTRIX to consistently deliver high-quality health content. KNOTRIX has independently developed the “Cheesecake” AIGC platform, which generates over 3 million words of video scripts annually and boosts per-capita video production efficiency by 50%. By offering intelligent content creation services to all health influencers, the platform has significantly enhanced workflow efficiency.

Built around an AI-centric technological framework, KNOTRIX is developing a whole-network supply chain BI analytics platform and an intelligent customer service response system, in addition to its proprietary AIGC platform, providing robust technical support for the health content ecosystem.

Commenting on this funding round, Ding Zhaoliang, Founder of KNOTRIX, stated: “In the future, KNOTRIX will focus on enhancing its professional expertise and service capabilities. By adopting a new approach that is trust-based, human-centric, and scientifically grounded, we aim to achieve greater success in the big health industry and become a next-generation operator of health-focused traffic ecosystems.”