Hanzandi Launches NLP-96 High-Throughput NGS Library Preparation Workstation, Pioneering Automation in Genomic Sample Processing

In recent years, high-throughput sequencing technology (NGS) are considered top-tier, asNGSFrom the gradual maturation of the technology, to gaining the attention of clinical experts, and ultimately to its clinical application,The substantial increase in sequencing throughput demands that upstream sample processing be as simple and rapid as possible to improveNGSThe work efficiency of the entire process.

Library preparation is an indispensable step in the NGS high-throughput sequencing workflow and one of the key determinants of NGS success. Although high-throughput sequencers have gradually become more automated and user-friendly, upstream sample preparation—particularly library construction—still requires precise and complex molecular biology procedures, characterized by being time-consuming, labor-intensive, and having low reproducibility. Automation is therefore key to optimizing throughput and cost-effectiveness.

HanZanDi Launches New ProductsNGS High-Throughput Library Preparation Workstation NLP-96, this isA high-throughput automated liquid handling workstation specifically developed for the automated NGS library preparation of up to 96 samples, suitable for the automation upgrade of most NGS library construction workflows on the market.

 NGS High-Throughput Library Preparation Workstation NLP-96

The NLP-96 enables flexible configuration of modules such as PCR instruments, temperature control units, magnetic racks, grippers, and shakers. With a single click to initiate the built-in protocol, it can process the entire NGS library preparation workflow for up to 96 samples or the purification workflow for up to 192 samples, easily achieving a “sample-in, result-out” workflow and reducing manual operation time by up to 90%. Meanwhile, stable and standardized automated operations significantly minimize errors introduced by manual handling, thereby enhancing experimental reliability and consistency.

96-Channel Pipettor

In terms of details, the NLP-96 is equipped with vertical sliding doors capable of hovering at any position, a high-precision robotic arm with a positioning accuracy of ±0.1 mm, four-color real-time status indicator lights, a large work surface with 28 standard plate positions, and a 96-channel pipettor.

Meanwhile, NLP-96 also features the following characteristics:

· Precision and Efficiency

28 standard plate positions + 96-channel pipetting module, effectively accelerating experimental throughput and supporting the consumables required for the entire NGS library preparation process of 96 samples or the purification process of 192 samples.

·Flexible Configuration

Built-in protocols for various library preparation kits enable rapid execution of experimental workflows by simply swapping modules on the workstation deck.

· Precision and Stability

Integrated multi-module design supports 24-hour experiments, ensuring high throughput, reproducibility, and accuracy in the NGS library preparation workflow.

· Easy to operate

Built-in programs, one-click startup, easy installation, open design, supports user-defined experimental workflows.

Based on the requirements of NGS library preparation experiments, Hanzandi offers two basic configuration options for its NLP-96 high-throughput NGS library preparation workstations:The instrument features a built-in PCR module capable of supporting the entire NGS library preparation workflow for up to 96 samples.、The external PCR instrument can accommodate the purification process for 192 samples.. Meanwhile, the team of professional application engineers at Hanzandi can also configure personalized solutions based on specific experimental protocols.

Built-in PCR Instrument: Configuration for the Full NGS Library Preparation Workflow of 96 Samples

External PCR Instrument: Configuration of 192-Sample Purification Protocols

Test results indicate that, compared with manual operations, automated library preparation reduces total turnaround time by 30% and manual hands-on time by 90%. The overall quality of libraries prepared using the automated workflow is superior to that of manual methods, meeting the requirements for next-generation sequencing (NGS).

DNA Library Preparation Quality Electropherogram

Overall,Hanzandi NGS High-Throughput Library Preparation Workstation NLP-96 is fully compatible with high-throughput gene sequencing library construction applications, including reproductive genetics (NIPT, PGS/PGD, early screening for genetic diseases), microbiology (identification of pathogenic microorganisms, viral integration detection, antimicrobial resistance testing), oncology (pan-cancer/specific cancer early screening, pharmacogenomic locus screening, HRD), immunology (multi-species immune repertoire sequencing, minimal residual disease in hematologic malignancies, HLA genotyping), general health (disease risk assessment, carrier screening, safe medication use), forensic science, molecular anthropology, agriculture, scientific research, and ecology.