VCBeat has learned that, recently,Rayleigh Optoelectronic Technology (Zhuhai) Co., Ltd. (hereinafter referred to as “Rayleigh Optoelectronics”)Announced Receipt ofGuangzhou Lihua Investment Co., Ltd. (hereinafter referred to as “Lihua Investment”)With an investment of several million yuan, both parties will join hands to open a new chapter of cooperation, jointly exploring new frontiers in the translation and industrialization of scientific and technological achievements.
Rayleigh Optoelectronics was established in 2023, byProfessors Zhuang Zhengfei and Chen Tongsheng, South China Normal UniversityCo-founded, it is a high-tech enterprise dedicated to the R&D, production, and sales of high-end FRET microscopy imaging systems, as well as providing scientific research testing services, and was included in the “2023 List of Specialized, Refined, Differential, and Innovative SMEs” published by the Department of Industry and Information Technology of Guangdong Province.

The company’s FRET (fluorescence resonance energy transfer) technology offers the unique capability to visualize molecular structure and function within living cells.The team has been deeply engaged in FRET technology for 24 years, developing a series of proprietaryFRET Hardware and Algorithms, formingQuantitative FRET Microscopy Imaging Analyzer for Live Cells, and Matching Microscope Light Sourceand other products. The company has secured more than 30 independent intellectual property rights closely related to its business operations and participated in the formulation of two IEC international standards. In addition, the company has also accumulated a reserve ofSIM-FRET Super-Resolution FRET Microscopy Analysis System, FRET Drug Screening System, Multi-Wavelength LED Light Source, High-End Microscope Frametechnological achievements ready for industrialization.
Rayleigh Optoelectronics’ independently developed and manufactured intelligent quantitative FRET microscopy imaging analyzer for live cells has successively won the Gold Award at the 1st China Postdoctoral Innovation and Entrepreneurship Competition (2021) and the Gold Award at the 1st Guangdong-Hong Kong-Macao Greater Bay Area Postdoctoral Innovation and Entrepreneurship Competition (2023). It has provided testing services to multiple institutions, including Tsinghua University, Shanghai Jiao Tong University, and Sun Yat-sen University Cancer Center. Internationally, it has pioneered the solution to the long-term quantitative analysis of molecular structure and function within live cells.

Selected Honors Awarded to Rayli Optoelectronics
Lihua Investment is an early-stage venture capital firm in China specializing in the commercialization of scientific and technological achievements, primarily serving technology transfer projects from universities and research institutes. Dedicated to building a support ecosystem for tech entrepreneurship, Lihua Investment is a pioneer and practitioner in the commercialization and industrialization of scientific and technological innovations. With comprehensive empowerment from Lihua Investment, Ruili Optoelectronics will accelerate its development across all fronts.
Prior to this, the company also received support from Zhuhai Zhengling Venture Capital Co., Ltd. and Zhuhai Abei Enterprise Management Consulting Center (Limited Partnership). Through in-depth collaboration with Lihua, Zhengling, and Abei Investments, Ruili Optoelectronics will be able to more fully leverage its technological advantages and market potential, provide more competitive products and solutions, and promote the transformation and industrialization of scientific and technological achievements.