Yixin Health Files IPO Prospectus: Customized Follow-up Platform Enhances Cardiology Workflow Efficiency

The Yixin App is dedicated to the cardiovascular niche, striving to build an online chronic disease management platform in this field. Gu Xi, its founder and CEO, stated that as a customized follow-up tool for a specialized domain, the Yixin App is committed to enhancing physicians’ practical work efficiency and optimizing the allocation of medical resources.

Customized Follow-up in Vertical Domains

In the field of internet healthcare, how to better utilize doctors’ “fragmented time” has long been a hot topic among mobile health companies. Guo Xi told VCBeat that during the Yixin team’s interactions with physicians, they learned that the current reality for many doctors is exhaustion to the point of collapsing in the operating room, as work causes them to neglect their personal lives, families, and even their own health. They are unwilling to devote their already scarce rest time to additional work.

In this regard, Yixin believes that if it is possible to leverage the internet toHelping physicians improve efficiency in clinical practice, then, the allocation of medical resources can be optimized without encroaching on physicians' rest time. Internet-assisted healthcare will bring greater efficiency improvements to the entire medical industry.

Gu Xi told VCBeat,“We do not use the Internet to encroach upon physicians’ fragmented time; rather, we leverage internet-enabled functionalities to enhance the efficiency of clinicians’ daily practice, ultimately benefiting both patients and healthcare providers.”

Statistics show that cardiovascular disease has become the leading cause of death in China’s healthcare sector, with as many as 290 million patients currently affected. However, a severe mismatch in key factors capable of improving patient prognosis and clinical outcomes—such as the number of physicians, chronic disease management systems, and post-diagnosis rehabilitation services—has emerged as the “Achilles’ heel” of China’s medical reform. In this context, deep vertical integration may represent the most significant innovation that internet healthcare brings to the medical industry.

Chronic diseases are characterized by their prolonged course, high patient stickiness, and severity (i.e., long treatment and recovery cycles, high frequency of care, potential lethality, and significant suffering). These characteristics create a substantial demand for post-diagnosis follow-up. While physicians generally have the willingness to manage patients after diagnosis, the extreme imbalance in the spatial, temporal, and experiential allocation of medical resources means they often lack the time, energy, and resources to conduct comprehensive follow-up care. This results in persistently high rates of patient loss during follow-up.

Chronic disease follow-up demands greater industry-specific expertise; otherwise, it is limited to basic time-based reminders and fails to genuinely improve the status quo. When narrowed down to a specific disease within a vertical specialty, variations in physicians’ treatment strategies and individual patient differences lead to significant distinctions in both the targeting and content of follow-up care. No universal follow-up template can adequately cover even a single disease category, let alone the entire field of chronic disease management.

Customized follow-up in vertical domains can be precisely tailored to specific diseases, research studies, hospitals, or even individual physicians. By integrating templates according to their actual needs, physicians can manage their patients more effectively, reduce patient attrition rates, and significantly support their scientific research endeavors.For patients, a customized post-discharge follow-up system enables access to personalized rehabilitation guidance from their surgical team, thereby improving prognosis, reducing subsequent healthcare costs, and fostering harmonious doctor-patient relationships.

Information, Disease Course, Follow-up, and Rehabilitation: Four Major Functional Modules

To address the current challenges in follow-up care, extensive industry expertise and abundant resources are essential. Yixin focuses on the cardiovascular specialty, providing physicians with efficient follow-up tools and offering patients comprehensive, attentive services throughout the entire post-diagnosis journey. More importantly, it establishes a one-on-one communication platform between patients and surgical teams.The physician-facing side of Yixin will provide doctors with services and support, including the dissemination of medical information, integration of patient disease trajectories, customized follow-up plans, and rehabilitation education. Corresponding patient-facing versions of these services will also be launched.

The medical information dissemination function adopts and integrates the capabilities of Yixin Network, *Yixin Review*, and the Yixin official WeChat account. It provides physicians with industry updates, domestic and international conference news, manufacturer information, clinical trials, and guidelines. For patients, it delivers personalized information tailored to individual hospitals, including admission instructions, preoperative education, hospitalization notices, postoperative care guidance, and departmental announcements.

The user course integration feature records and consolidates the entire diagnostic and treatment journey, from the initial consultation through referrals. It offers functionalities such as user tagging and flexible group segmentation, providing a clear overview of diagnoses, reports, and follow-ups, while ensuring that medical records are accessible regardless of time or location. For physicians, the app’s doctor-patient verification process enables them to understand patient profiles and manage patient groups efficiently without disclosing personal information, thereby minimizing unnecessary disturbances. For users, there is no longer any concern about losing medical reports; cloud-based information storage allows them to monitor their clinical course anytime and anywhere.

The customized follow-up feature is designed to enable personalized follow-up care. It goes beyond simple appointment reminders by having patients respond to a set of professional follow-up questions. Building on insights gained from the follow-up templates and systems of the Cardiovascular Medical Center, and integrating clinical needs, we provide physicians with exclusively customized patient follow-up management templates. This helps doctors manage their patients more effectively and improve the efficiency of patient follow-up.

The rehabilitation patient education function offers more specialized and personalized rehabilitation guidance. Through patient management groups, physicians can provide targeted guidance on medication, exercise, diet, lifestyle habits, and psychological well-being to individual patients, thereby improving adherence to rehabilitation management. Patients can also identify physicians who are familiar with their disease course and follow-up records, enabling them to ask more professional questions and receive timely rehabilitation and educational guidance.

Gu Xi revealed that the aforementioned features are to be implemented in version 1.0 of the Yixin APP, which is currently undergoing internal testing and refinement. The app is scheduled for official release on major app stores in mid-November. In the future, the corresponding functional modules of the Yixin APP will undergo continuous upgrades and updates. By integrating with emerging technologies, the app will achieve remote, convenient, and real-time collection, organization, and analysis of user diagnostic and treatment data. It aims to benefit clinical practice and scientific research by constructing professional-grade cardiovascular medical big data, while continuously introducing new modules that combine online and offline services in a complementary manner to realize one-stop, full-cycle management of chronic diseases.

Currently, Yixin has partnered with "Palm ECG," a smart medical-grade wearable ECG company.(For details on “Pocket ECG,” please refer to the VCBeat article “VB Group Interview No. 6 | Pocket ECG · Song Yinfeng: Patient-Centric Approach—How Mobile ECG Products Address the Pain Points of Atrial Fibrillation Patients”)Establish a partnership to create a new online post-diagnosis service model for cardiovascular care, integrating hardware into a unified platform.

It is understood that the Yixin brand originated from Yixin.com, which was founded in 2000 as China’s first medical website dedicated to the field of cardiovascular medicine and has a history of 15 years. With advances in medical diagnostic and therapeutic technologies as well as internet technology, Yixin has successively established platforms such as *Yixin Commentary*, Yixin Mobile Report, Yixin Weibo, and Yixin WeChat. These platforms provide functions including the dissemination of cutting-edge medical information, tracking of conference developments, reporting on clinical research, case sharing, and publication of guidelines.

Within the Yixin team, CEO Gu Xi previously held marketing management positions at Johnson & Johnson Medical and Abbott’s Vascular Devices division, while the other founders come from traditional medical manufacturing, clinical research organizations (CROs), and healthcare investment firms.