Yanyunbao Files Prospectus for Smart Maternity Diagnostic and Post-Diagnosis Healthcare Platform Targeting Women of Childbearing Age

Yan Yun Bao You Pregnancy Preparation Hub is a smart diagnostic and post-diagnosis medical service platform specifically tailored for women of childbearing age, integrating services such as HCG (early pregnancy) testing, menstrual cycle management, LH (ovulation) testing, medical guidance, and health consultations. Through this platform, users can connect with maternal and child health centers, specialized obstetrics and gynecology hospitals, and distinguished physicians. It establishes a comprehensive system linking hospitals, doctors, and home-based self-testing, forming an interactive smart specialty medical diagnostic system that provides professional services to women during their preconception and pregnancy periods.

Precision Testing + Intelligent Analysis

Yanyunbao’s WeChat platform uses self-test results from families (users) as an auxiliary basis for physicians’ clinical diagnosis. Leveraging its independently developed T-LINE smart diagnostic technology for data analysis, the platform delivers medical-grade, precise test results and provides professional, accurate, considerate, personalized, high-quality healthcare services based on these results.

In addition to determining pregnancy status through its intelligent diagnostic analysis system, Yanyunbao can also inform users of the conception date, gestational age, and expected due date. “By conducting continuous monitoring starting one week before the expected onset of menstruation, the accuracy rate can reach 99%. Compared with traditional test strips, Yanyunbao’s greatest advantage is that it directly provides the test results, eliminating the need for users to interpret the results themselves and thereby avoiding various unnecessary troubles caused by misinterpretation or false readings. Meanwhile, Yanyunbao also retains the advantages of traditional test strips, allowing for direct sampling from the urine stream, which is convenient and efficient,” Long Guoliang, CEO, told VCBeat.

Selected Dominant Follicles — Intelligent LH Monitoring

Within the cohort of developing follicles during the menstrual cycle, the follicle with the lowest threshold is preferentially selected to become the dominant follicle. By days 13–18, the dominant follicle enlarges to approximately 18–23 mm, at which point it is considered a mature follicle. If ovulation occurs from an immature or poorly developed follicle, it can lead to reduced oocyte fertilization capacity. Even if fertilization and implantation occur, impaired subsequent differentiation and development may result in infertility or spontaneous abortion.

“Therefore, the most fundamental aspect of preconception care is monitoring ovulation quality, which requires medical-grade products for detecting ovulation-inducing hormones. Luteinizing hormone (LH) is a specific marker for monitoring ovulation and is medically referred to as the ‘gold standard.’ The anti-interference capability, specificity, and medical reliability of LH testing are incomparable to so-called methods such as calculation, empirical estimation, basal body temperature, or subjective sensation. For users, the core value of health-related products lies in accuracy; however, eugenics and optimal childbearing require not only accuracy but also the scientifically guided selection of dominant follicles for conception, thereby nurturing babies with the greatest potential,” explained Long Guoliang.

“Yanyunbao utilizes proprietary companion test strips and a platform-based diagnostic system to accurately predict ovulation timing with hour-level precision. Furthermore, its dynamic curve magnitude analysis system helps identify the highest-quality oocytes in a given cycle, providing a scientific basis for preconception care and promoting eugenics and healthy childbirth.” When discussing Yanyunbao’s unique advantages, Long Guoliang highlighted the self-developed proprietary companion test strips, which deliver more accurate test data and better integrate with subsequent data analysis.

Embryonic Development Monitoring — Intelligent HCG Monitoring

“Every pregnancy carries a 1% risk of ectopic pregnancy, and every conception faces the risks of early miscarriage and missed abortion. Every formed fetus is at risk of late miscarriage and preterm birth, and every full-term fetus confronts dystocia—the final hurdle before human birth. Nearly 15%–20% of pregnancies, despite the initial joy, end in tragedy. The incidence of spontaneous abortion ranges from 15% to 40%, with over 80% occurring in the first trimester. From a medical evidence perspective, the first three months of pregnancy are the most critical period for fetal development, as more than 80% of adverse events occur during this time,” introduced Long Guoliang.

When monitoring embryonic development, the key indicators are HCG (human chorionic gonadotropin) and P (progesterone), with hormone levels and their rate of increase being critical points of focus.

Compared with B-mode ultrasound: B-mode ultrasound requires a hospital visit for examination. In early pregnancy, due to the short duration of amenorrhea, it may not be visible even with B-mode ultrasound. Ultrasound has certain biological effects; although there is currently insufficient evidence to prove that diagnostic ultrasound is harmful to the fetus, caution should still be exercised when using it on early embryos.

Compared with serum progesterone: A progesterone level higher than 25 ng/mL suggests a viable intrauterine pregnancy; a level lower than 5 ng/mL indicates embryonic demise. However, for progesterone levels between 5 and 25 ng/mL, continuous dynamic monitoring is required, as it is not possible to determine whether the intrauterine pregnancy is viable, if there is abnormal fetal development, or if an ectopic pregnancy is present.

“Yanyunbao utilizes a proprietary test strip and diagnostic system to continuously monitor HCG growth rates, enabling timely screening for abnormal early embryonic development. This facilitates early detection and treatment, minimizing potential harm.” Long Guoliang expressed strong confidence in selecting HCG as the target analyte, believing that Yanyunbao can thereby earn the trust of women during preconception and pregnancy.

Comprehensive, Thoughtful Guidance — Online Consultations with Professional Physicians and Platform Customer Service

The platform’s professional customer service team collaborates with renowned obstetricians and gynecologists from leading specialized hospitals in China to provide expert consultation and guidance, helping individuals during pregnancy navigate testing with clarity and confidence. When Yan Yun Bao detects hormonal abnormalities in users, it promptly conducts follow-up communications to offer comprehensive services for optimal preconception care and pregnancy preparation.

Meanwhile, Yanyunbao also offers customized reproductive health services, providing users with guidance on menstruation, preconception care, pregnancy and childbirth, and prenatal check-ups. In addition, doctors provide online consultation and appointment registration services, enabling users to receive high-quality, professional guidance based on precise personal data, whether at home or in the hospital.

80 million potential customers annually

According to the 2013 demographic structure data from the "China Population Statistical Yearbook," China has 350 million women of childbearing age (18–45 years), with an annual net population increase of 20 million. Statistical data show that the live birth-to-pregnancy ratio is 26%, meaning that 74% of pregnancies end in abortion or other outcomes. The total number of pregnancies nationwide is approximately 80 million per year, which translates to roughly 80 million instances of post-diagnosis medical services annually. This vast volume of post-diagnosis care represents a huge market, offering significant opportunities for high-quality prenatal and reproductive health services. It was within this market that Long Guoliang identified an opportunity.

Attracting User Attention from Multiple Angles

“Yanyunbao has focused on product development and partnerships to attract user attention and build its user base. By encouraging users to engage with the platform through various channels, it aims to highlight and promote the product’s unique advantages, foster positive word-of-mouth, and continuously expand its user count, thereby serving more individuals during their preconception and pregnancy periods,” introduced Long Guoliang, outlining several key strategies Yanyunbao employs for user acquisition.

1. From a product perspective: Initially, QR codes printed on products serve as user entry points to build product awareness and reputation, drive traffic to the platform, establish influence, and create user access channels along with viral propagation loops (achieved by binding QR codes to smart diagnostic services). Following the official WeChat account enables direct communication with and service delivery to users, fostering two-way interaction.

2. Third-Party Integration: The T-LINE Smart Diagnostic System is a lightweight web-based application that can be seamlessly integrated into third-party platforms. It has already been launched on the JD Daojia app and the Yunyubang WeChat official account, and collaborations with hospitals such as Baodao Obstetrics and Gynecology and Mary Maternal and Child Health Hospital are actively underway. This initiative aims to provide users with more effective and convenient services while driving traffic and promoting products for partner platforms, achieving a win-win outcome.

3. Big Data Mining: By collaborating with partners across or within the industry, we provide third parties with big data analytics and user access portals to generate revenue and acquire users, thereby attracting new users in return and creating a closed-loop business model. Meanwhile, we offer big data support for the development of premium maternal health products.

Core Team

Long Guoliang, founder of Yanyunbao, is the holder of multiple national patents and trademarks. His technical expertise lies in in vitro diagnostics (IVD), with extensive familiarity with the research and development, manufacturing, sales, and operational processes of medical IVD reagent products. He also possesses rich experience in the operation of medical institutions and corporate management.

Technical Director Sixi holds a master’s degree and has previously worked at companies such as ZTE Corporation. He possesses a strong technical foundation and extensive product R&D experience in smart hardware and interactive user experiences.