Eggshell Weekly Report 0709: 19 Global Healthcare Financing Deals Announced; KingMed Diagnostics Passes IPO Review

Seven Ministries Issue Document: Public Hospitals, the “National Team,” Must Implement Healthcare Reform by End of September【[Healthcare Reform]

On July 4, seven ministries and commissions, including the State Council Office of Healthcare Reform, the National Health and Family Planning Commission (NHFPC), and the Ministry of Finance, jointly issued a notice explicitly requiring that all hospitals directly affiliated with the NHFPC and the National Administration of Traditional Chinese Medicine, as well as university-affiliated hospitals under budgetary management, must fully participate in local comprehensive public hospital reforms by September 30, 2017.

Wanda Invests 50 Billion Yuan in Kunming Medical Project【【Medical Real Estate】

According to the official website of Wanda Group, on July 3, Wanda Group signed three new investment projects in Kunming. Among them, Wanda plans to invest RMB 50 billion in Kunming City to build a world-class medical and big health industrial park centered on healthcare and wellness, while integrating functions such as sports, health preservation, vacationing, commerce, business, and residential living.

Parting Ways with CR Phoenix: CITIC Medical Plans Backdoor Listing via CITIC Offshore Helicopter[Listed Companies]

The day before news spread that CITIC Medical had withdrawn from the deal with China Resources Phoenix, its sister company, CITIC Offshore Helicopter Co., Ltd. (hereinafter referred to as “CITIC Offshore Helicopter”), issued an announcement stating that its shares were suspended due to the planning of a major matter. On July 1, CITIC Offshore Helicopter, which had been continuously suspended from trading, publicly confirmed that the target of its major asset restructuring was CITIC Medical’s assets.

BeiGene and Celgene Reach Nearly $10 Billion Oncology Drug Partnership【[Pharmaceuticals]

The two parties will jointly develop and commercialize BeiGene’s PD-1 antibody, BGB-A317, for the treatment of solid tumors. In addition, BeiGene will take over Celgene’s operations in China and hold exclusive rights to Celgene’s approved products in the country. The transaction includes a $263 million upfront payment, a $150 million equity investment, and up to $980 million in future milestone payments and royalties.

Dongcheng Pharmaceutical【[Investment] 

Dongcheng Pharmaceutical Discloses Restructuring Plan on the Morning of the 30th, Intending to Acquire Andike for RMB 1.6 Billion

Wanda Group【[Investment] 

On July 3, Wanda Group signed three new investment projects in Kunming. Among them, Wanda plans to invest RMB 50 billion in Kunming to build a world-class medical and general health industrial park centered on healthcare and wellness, while integrating functions such as sports, regenerative care, vacationing, commerce, business, and residential living.

Neptunus Bio【[Market Launch]

Neptunus Biotech Plans to Invest RMB 295 Million in a Collective Fund Trust Established by National Trust Co., Ltd. to Subscribe for Limited Partner Interests in Shenzhen Maideixin No. 1 Fund Partnership (Limited Partnership)

Hanyu Pharmaceutical【[Investment]

Hybio Pharmaceutical, in partnership with Guangzhou Minsheng Industrial Investment and Zhongyu Capital, established the Hanguang International Pharmaceutical Venture Capital Fund and the Hanyu Pharmaceutical Industry M&A Investment Fund, with respective sizes not exceeding RMB 300 million and RMB 2 billion. Additionally, Hybio’s subsidiary, Hong Kong Hybio, co-established a fund with Zhongyu Capital, with a total fundraising size not exceeding EUR 50 million.

Kangmei Pharmaceutical【[Self-built]

Kangmei Pharmaceutical announced that it had received approval from the Guangdong Provincial Food and Drug Administration to conduct pilot research on traditional Chinese medicine (TCM) formula granules within the province. The Kangmei TCM formula granules project covers a total land area of approximately 12,000 square meters, with 12 new production lines to be constructed. The annual extraction capacity for TCM will reach approximately 6,000 tons. The company plans to develop around 450 varieties of TCM formula granules for production, with an annual output of approximately 2.4 billion packets.

AI-Controlled Biological Heredity【Application Area: Genes]

It is reported that Alibaba Cloud is internally running a project to explore AI-controlled biological genetics. The project has just completed predictions of whole-genome traits for Xiaomi, with an accuracy rate exceeding 90%.

H7N9 Subtype Avian Influenza Vaccine[Application Field: Avian Influenza]

H7N9 Subtype Avian Influenza Vaccine Developed by Chinese Scientists Enters Production and UseThe National Avian Influenza Reference Laboratory employed reverse genetics technology to develop a safe and highly efficient master seed virus for the H7N9 inactivated vaccine. Rigorous evaluations demonstrated that the new vaccine strain is non-pathogenic to both avian species and mammals. The first batch of vaccines was delivered to Guangdong, Guangxi, and other regions by the end of June for pilot immunization programs.
    

Advanced Maternal Age[Application Area: Eugenics and Healthy Childbearing]

A recent joint study published in the International Journal of Epidemiology in the United Kingdom shows that children born to older mothers today are smarter than those born to younger mothers, compared to 40 years ago. The study states that this shift is due to changes in older mothers themselves. Today, older mothers often have advantages over younger mothers, such as being well-educated, not smoking during pregnancy, and having more successful careers. This was almost impossible in the past.

Chromosome Technology[Application Field: Anti-Aging]

German Scientists Discover That Premature Shortening or Damage to Protective Telomeres at Chromosome Ends Triggers Cellular Repair Mechanisms to Prevent Premature Senescence, Advancing Understanding of Cellular Aging, Human Aging, and Cancer

Artificially Cultured Cell Tissues[Application Area: New Drug Testing]

Scientists at the University of Cambridge in the United Kingdom published a paper in Nature Medicine, reporting that they had cultivated 3D biliary epithelial cell structures in the laboratory and successfully transplanted them into mice, where they developed into functional bile ducts. This significant breakthrough in the field of artificial bile ducts could potentially replace liver transplantation for treating pediatric patients with liver disease in the future. In addition to their use in transplantation, these artificial bile ducts provide new models for studying the pathophysiology of biliary diseases and testing novel drugs.

Replacing Traditional Contrast Agents with Sugar[Application Area: Contrast-Enhanced Magnetic Resonance Imaging]

Researchers from the German Cancer Research Center and Heidelberg University Hospital have announced the successful implementation of a novel enhanced magnetic resonance imaging (MRI) technique. This method utilizes a sugar solution, which is virtually harmless to the human body, to amplify MR signals in target areas, thereby replacing traditional contrast agents that may pose potential health risks.

Male Age Affects IVF Success Rates[Application Area: IVF]

At the recent European Society of Human Reproduction and Embryology (ESHRE) Annual Meeting, researchers from Harvard University presented findings from a study involving 19,000 in vitro fertilization (IVF) cycles, indicating that advanced paternal age also reduces the success rate of IVF. The results underscore that men should also plan for parenthood at an earlier age!